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By Desmond Hansen
December 1, 2015

Growth Factor-9

Growth Factor-9
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Created by Novex Biotech, Growth Factor-9 is a recently released HGH secretagogue designed to maximize your physical performance.

Advertisements promise this “complex hormone antecedent” is strong enough to “unleash your total performance and anti-aging potential.” This is supposed to give you the ultimate body you deserve.
Recent press releases go so far as to claim that “Growth Factor-9 is too good to be true.”[1]

And is it?

To find out if Growth Factor-9 is as good as manufacturers would have us believe, I took a closer look at what this tiny pill could really do. . .

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What’s the Connection Between SeroVital and GF-9?

The first thing that caught my eye when I looked at the ingredient label was SeroVital plastered across the proprietary blend.

SeroVital, an anti-aging supplement, is sold by SanMedica and backed by the Sierra Research Group. So why is SeroVital making an appearance in a sports product?

Kerry Pack, a communications specialist with Sierra Research Group explains the connection between the two companies:

“With all the recent media coverage, sales have gone through the roof and our suppliers have been having trouble keeping up . . . So we’re thrilled to announce that we’ve recently issued a … license to sports supplement company Novex Biotech, which will sell the compound as Growth Factor-9 exclusively at GNC. . .This will give consumers an extra avenue to get their hands on our proprietary formula.” [2]

SierraResearchGroup.com goes on to state, “SanMedica is in the final stages of ramping up production of its SeroVital-hgh, the first of the officially licensed brands to hit the market. Novex Biotech, a leader in the fitness and bodybuilding arena, is not behind with its offering, Growth Factor-9, which will be available in GNC Stores October 2012.”[3]

Key Ingredients

Growth Factor-9 offers 2.9 grams of SeroVital-hgh. Essentially it’s the same product, but with a different name to attract a larger market.

So what’s inside this oh-so-popular blend?

L-Arginine. Arginine is a precursor to nitric oxide, a compound that relaxes blood vessels and improves circulation. Many body builders turn to arginine to improve performance and accelerate muscle growth.

However, studies show arginine is also an effective HGH releaser. When taken in 5 to 9 g doses, arginine increases HGH production by as much as 100%. And when combined with exercise, that percentage nearly doubles! [4]

Unfortunately, Growth Factor-9 only contains 2.9 g of the SeroVital formula, which is only a fraction of the recommended arginine dosage. Consequently, arginine must be combined with an equally effective amino acid to provide any benefits.

L-Lysine. Many experts believe lysine combined with arginine is the perfect option. One study shows 1200 mg lysine combined with 1200 mg arginine is enough to increase HGH production and optimize insulin efficiency. [5]

Added together, this totals to 2.4 g out of the 2.9 grams in Growth Factor-9, assuming the product contains the clinically proven amount.

However, this only leaves .5 grams to divide among the remaining ingredients, which makes me question the effectiveness of the ingredient concentrations. Did Growth Factor-9 divvy the ingredients out evenly and use lower, slightly ineffective concentrations for everything? Or did Growth Factor-9 use two effective concentrations and skimped out on the remaining ingredient concentrations?

Due to the nature of the proprietary blend, it’s impossible to tell. . .

Furthermore, lysine studies are fairly mixed. While the above lysine-arginine combination offered positive results, some studies revealed lysine supplementation to have no effect on HGH at all. . [6]

N-Acetyl L-Cysteine. NAC is a modified cysteine molecule which acts as a powerful antioxidant. It eliminates free radicals, reduces oxidative stress on cells, and protects against cardiovascular disease.

This molecule metabolizes into glutathione and glutathionine peroxidase.

Rob Keller, MD, believes glutathione is clinically proven to increase Human Growth Hormone markers DHEA and IGF-1. [7] But, “Dr” Keller is selling glutathione products and there is no clinical information validating this claim.

L-Glutamine. Glutamine is the most common amino acid found in muscle tissue. It is essential for nitrogen transportation and protein synthesis. Experts agree glutamine supplementation minimizes muscle breakdown and improves protein metabolism.

Additionally, studies show glutamine supplementation significantly increases circulating HGH levels within 90 minutes after ingestion. [8]

On the other hand, these studies often involved 2 g glutamine, and I doubt Growth Factor-9 has this much.

OxoProline. Not a lot of information is available on oxoproline. This molecule is a glutamic acid derivative that may exhibit antioxidant properties. However, there are no clinical studies linking oxoproline to HGH production.

Schizonepeta. Like oxoproline, not a lot of clinical trials have been conducted on schizonepeta. This herb is traditionally used to treat inflammation and contains compounds which may inhibit cytokine release. There are no studies on Schizonepeta’s potential effects on HGH.

Should You Trust the Study?

Novex Biotech and SanMedica both reference a study conducted on SeroVital. In this study, researchers found SeroVital increased HGH production by as much as 682% within 120 minutes after ingestion.

Additionally, manufacturers point out that the “study’s findings have been reviewed by the Obesity Society and were accepted for public presentation at the Obesity Society’s prestigious 30th Annual Scientific Meeting.”

Sounds pretty impressive, doesn’t it?

Dr. Peter Griffiths, author of How to Burn More Fat 24 Hours a Day. . .Without Diet or Exercise, has a contradictory opinion:

“The studies behind it are not solid. In fact there is only one study. This was presented as an abstract at a conference meaning it has never been published in any scientific journal or subjected to any scrutiny by medical professionals. This is a common tactic among supplement companies who want to give pseudo-scientific backing to their product.

“Secondly even if this product works as claimed, their own study admits it is equivalent to 0.06iu of injected GH, a dose which anyone who has used real injected GH will tell you has virtually no fat loss effects.” [9]

Does Dr. Oz Endorse Growth Factor-9?

Dr. Oz does not promote or endorse any specific products. Despites this, many advertisements claim Dr. Oz was excited about the research behind SeroVital’s (and Growth Factor-9’s) ability to boost HGH.

On his show, Dr. Oz states, “A recent study showed that patients given a special blend of amino acids saw their HGH levels spike more than 6x the levels they had at the beginning of the study.” [10]

While this study seemed to provide similar results to the ones advertised by Growth Factor-9, Dr. Oz did not provide specific references to confirm the product was the same.

Potential Side Effects and Risks

As far as I can tell, Growth Factor-9 does not result in any severe negative side effects when used correctly. The ingredients are safe to use on a regular basis.

However, consumers should not take more than 4 capsules daily. Exceeding the recommended dosage increases your risk of negative side effects.

Although amino acids such as arginine are safe to use in small amounts, taking too much at once may result in abdominal pain, bloating, diarrhea, and vomiting.

Furthermore, Growth Factor-9 may interact negatively with certain medications. To ensure safety, consult your doctor before making any changes to your current diet or exercise program.

How to Get the Best Results

According to NovexBiotech.com, Growth Factor-9 has a few catches:

1. Growth Factor-9 must be part of a total program – it won’t help you lose weight if you don’t eat right and work out
2. Growth Factor-9 must be taken on an empty stomach. You can take 4 capsules first thing in the morning and then not eat anything for two hours, or take it at night, at least two hours after your last meal before you go to bed.

Best Places to Buy Online

The third “catch” listed on NovexBiotech.com involves the hefty price.

“Last but not least, while Growth Factor-9 is far less expensive than prescription HGH injections, it’s still not cheap. . .GF9 will cost you about $100 a month.”

Even shopping through different distributors, I couldn’t find Growth Factor-9 for less than $90. If you can afford it, you may want to buy Growth Factor-9 from the following sites:

• NovexBiotech.com: $99 (+$6.95 in shipping)
• GNC.com: $99.99
• eVitamins.com: $99.99
• LuckyVitamin.com: $99.99

Return Policies and Customer Service

Supposedly Novex Biotech offers a 100% money back guarantee, but the website doesn’t provide any additional specifics on their return policies.

I sent an email to customer service asking about how to make a return, and I’ve yet to receive a response to my inquiry.

Pick It or Pitch It?

Growth Factor-9 does have a few good amino acids, but they’re not used effectively to provide you the age-defying results you’re looking for.

HGH supplements like Growth Factor-9 are severely overhyped. Also, I don’t entirely trust the manufacturers to follow through with their promises (or their guarantee).

Consequently, I don’t feel comfortable recommending Growth Factor-9. There are more reliable, more affordable supplements available that offer better results.


[1] “Is There a Sports Growth Hormone Conspiracy, asks Novex Biotech?” PR Newswire.com. Jan 11, 2013. Available from: http://www.prnewswire.com/news-releases/is-there-a-pro-sports-growth-hormone-conspiracy-asks-novex-biotech-186426391.html

[2] Johnsen, Michael. “Sierra Ressarch Labs licenses distribution of SeroVital-hgh through GNC to Novex Biotech.” Drug Store News. Dec 27, 2012. Available from: http://drugstorenews.com/article/sierra-research-labs-licenses-distribution-serovital-hgh-through-gnc-novex-biotech

[3] “Sierra Research Group Officially Licenses New “Youth Pill.” Sierra Research Group LLC. Sept. 21, 2012. Available from: http://sierraresearchgroup.com/press/sierra-research-group-officially-licenses-new-youth-pill/

[4] Kanaley JA. “Growth hormone, arginine and exercise.” Current Opinion in Clinical Nutrition & Metabolic Care. 2008 Jan;11(1):50-4. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18090659

[5] Isidori A, Lo Mocao, Cappa M. “A study of growth hormone release in man after oral administration of amino acids.” Current Medical Research & Opnion. 1981;7(7):475-81. Available from: http://www.ncbi.nlm.nih.gov/pubmed/6790230

[6] Corpas E, Blackman MR, Roberson R, Scholfield D, Harman SM. Oral arginine-lysine does not increase growth hormone or insulin-like growth factor-I in old men. J Gerontol. 1993;48(4):M128-33. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8315224

[7] Keller, Rob. “Glutathione.” Max Health for Life. Available from: http://maxhealthforlife.net/

[8] Welbourne TC. “Increased plasma bicarbonate and growth hormone after an oral glutamine load.” American Journal of Clinical Nutrition. 1995 May;61(5):1058-61. Available from: http://www.ncbi.nlm.nih.gov/pubmed/7733028

[9] “New Serovital HGH Product?” Iron Magazine. Nov. 11, 2012. Available from: http://www.ironmagazineforums.com/supplements/170890-new-serovital-hgh-product.html

[10] Oz, Mehmet. “Recharge Your Body in 5 Ways in 5 Days!” The Dr. Oz Show. Available from: http://www.doctoroz.com/episode/recharge-your-body-5-ways-5-days?video=15367

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Growth Factor-9 Customer Reviews

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rana Says:

Consequently, I don’t feel comfortable recommending Growth Factor-9. There are more reliable, more affordable supplements available that offer better results what are they?????

March 23, 2013 at 5:05 pm

admin Says:

Rana, I’m sorry about your confusion. You can read more about the top recommended supplements by going to the homepage. There are 10 products that offer pretty good results. Hope this helps!

March 26, 2013 at 2:51 pm

Stephen Reichard Says:

Most of the active ingredients used in GF-9 formula can and should be purchased individually at your favorite vitamin shop. Then you can adjust the most effective dosage to suit your body and life style. Not to mention that the cost will be significantly cheaper for much more product. Check out the list of products needed for HGH production at Dr. Mike, The Body Well, (10 Ways To Increase Your Human Growth Hormone (HGH) Levels Naturally. Age well and stay thirsty my friends!

January 6, 2014 at 4:36 pm

tyler Says:

I have used GF9 and I love my results in lean muscle growth but Lately I’ve been noticing I get really sore almost immediately after working out and have really bad heart burn, toys had been going on for 2 weeks in my second month of taking it and I’m only 18. I don’t know if the factor 9 is linked because this didn’t happen the first month I started but I also two weeks off it before I could buy my next months supply then the heart burn and soreness started happening. Again don’t know if it’s linked but something to keep an eye on.

April 5, 2014 at 1:03 am

tyler Says:

I apologize for my typo in the last post “toys had” should be “this has.”

April 5, 2014 at 1:06 am

Daniel Says:

Tyler: not recommended for anyone under the age of 25. Read the label.

May 9, 2014 at 11:46 am

Joe Says:

I have been taking GF9 for a year. Well i Stopped for 3 months after taking it for 8 months straight. No I am back and have been taking it for 3 months. I am 45 years of age and GF9 makes me feel way younger than that. The first thing I notice 3 or 4 days after I started taking it, was the really deep sleep at night which made me feel so rested the next day. Very vivid dreams that I hadn’t had since I was a teenager. I play sports and my recovery time dropped to zero. No pain after a 90 min soccer game. It gives me a lot of energy.
The skin on my face is tighter and I look ten years younger. Before I started taking it I was starting to look my age.
The price is a little too high, but it’s worth it. I started working out again and have the energy of a young man in his 20s.
My GF takes it as well but it took her longer to start seeing results. I guess it all depends on your body type and all the toxins collected by your body over the years.
When I stopped taking it for 3 months, I started to feel old again…. and worse, my skin was looking dry and old…. that’s the reason I went back to it. I guess when you feel and look good for a while, you start to take it for granted. Thats why I stopped taking it. From now on, Im gonna take it as long as I can afford it.

May 12, 2014 at 7:57 pm


I have got to tell you all I started Growth Facter-9 Friday, was so sore from work, I was in GNC and though twice, and said I need something that’s going to do the trick, not to mention, my goal is 100hrs next check, and really today right now I feel explosive, Like I can knock people out in the cage with my training, I feel on top, tonight I had to look in the mirror and say damn look at that big buff guy, I bench 400 pounds run the 400 in 55 seconds or less, and the good thing is its legal, I can fight in the cage with this and its not steroids, Its natural, what I noticed was when I was taking Amino 2222 from GNC it help more, no pain just feeling on top of the world, It also helps with the libido and tonight I feel like I can lift the back end of a truck up its good stuff.

June 17, 2014 at 10:15 pm


I love Growth Factor-9 makes me feel on top of the world

June 17, 2014 at 10:16 pm

Rob Ratliff Says:

I am 44 years old. I started taking growth factor 9 and it took about 4 days and then I started feeling much better as far as my energy throughout the day. Before I started taking it, it seemed like I needed a nap every day. Once I started taking it regularly, I just didn’t feel as tired. I felt like I had energy again. I have also noticed that my muscles seem leaner and I’m starting to look more toned and defined. The funny thing is, I rarely workout. After reading your report and seeing that exercise can really help improve on the affects, I’m going to start working out every day. I can’t say it’s going to work for everyone, but I like the stuff, I really do.

September 16, 2014 at 11:53 pm

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